3-MeO-PCP.

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(3-MeO-PCP) is a dissociative anesthetic drug that is sold online as a research chemical. The effects are often described as being more euphoric and mentally clearer than many related compounds.

History

A 1965 article published by Maddox described the synthesis of 2-MeO-PCP and 4-MeO-PCP. Preparation of 3-MeO-PCP was described later in 1979 by Geneste et al.

The compound was first synthesized in 1979 to investigate the structure-activity relationship of phencyclidine derivatives. The activity of 3-MeO-PCP in man was not described until 1999 when a chemist using the pseudonym John Q. Beagle wrote that 3-MeO-PCP was qualitatively similar to PCP with comparable potency.

Dosage

3-MeO-PCP, like PCP is active in the single milligram range and therefor can be hard to accurately measure.

Most if not all consumer-grade jewelry-scales advertised as working at the 0.001g (mg) range are not reliably accurate enough to measure quantities weighing less than around 15-25 mg depending on the model and calibration. With a drug as potent as 3-MeO-PCP a small discrepancy in measurement can make a world of difference in physical and mental response to the dose. It is for these reasons that it would be in one’s best interest to use a volumetric dose measurement technique as outlined in this guide.

Oral

Threshold	1.5-3 mg
Light	3-5 mg
Common	5-10 mg
Strong	10-15 mg
Heavy	15-18 mg+

Insufflated

Threshold	1-2 mg
Light	2-5 mg
Common	5-8 mg
Strong	8-12 mg
Heavy	12-15 mg+

 

Oral

Onset	20-40 minutes
Total	3-5 hours +/- 60 minutes, dependent on dose.
After-effects	2-48 hours

Insufflated

Onset	10-30 minutes
Total	2-4 hours +/- ~30 minutes, dependent on dose.
After-effects	2-48 hours

Effects

Positive

• Increase in energy / stimulation

• Euphoria

• Pleasant mental and/or body high

• Music appreciation

• Disconnected thoughts

• Sense of calm

• Increased sociability, loss of inhibitions

• Closed and open-eye visuals

• Shifts in perception of reality

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